Recent Publications

Orally bioavailable small-molecule inhibitor of transcription factor Stat3 regresses human breast and lung cancer xenografts
Zhang X, Yue P, Page BD, Li T, Zhao W, Namanja AT, Paladino D, Zhao J, Chen Y, Gunning PT, Turkson J.
Proc Natl Acad Sci U S A. 109(24):9623-8, 2012.

Targeted inhibition of TET1 transcription as a potent therapeutic strategy for acute myeloid leukemia.
Jiang X, Hu C, Ferchen K, Nie J, Cui X, Chen C-H, Zuo Z, Seibel W, Skibbe JR, Cheng L, Tang Y, Wunderlich M, Reinhold WC, Arnovitz S, Ulrich B, Lu J, Weng H, Su R, Huang H, Dong L, Wang Y, Li C, Qin X, Mulloy J, Zheng Y, Diao J, Jin J, Li C, Liu PL, He C, Chen Y, Chen J.
Nature Communications., 8(1):2099, 2017.

(Cell Chemical Biology, 26:278-288.e6, 2019; Nature Communications, 9:5145, 2018).
(Proceeding of the National Academy of Sciences, 101:14373-14378, 2004).
(Nature Communications 7: 12326, 2016).
(Nucleic Acids Research. 46: 7108–7123, 2018)
(Nature Communications, 9: 3001, 2018)
(Nature Communications, 9:4870, 2018)